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Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA.
Nicholls, Thomas J; Nadalutti, Cristina A; Motori, Elisa; Sommerville, Ewen W; Gorman, Gráinne S; Basu, Swaraj; Hoberg, Emily; Turnbull, Doug M; Chinnery, Patrick F; Larsson, Nils-Göran; Larsson, Erik; Falkenberg, Maria; Taylor, Robert W; Griffith, Jack D; Gustafsson, Claes M.
Afiliação
  • Nicholls TJ; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden.
  • Nadalutti CA; Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA.
  • Motori E; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.
  • Sommerville EW; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Gorman GS; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Basu S; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden.
  • Hoberg E; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden.
  • Turnbull DM; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Chinnery PF; Department of Clinical Neurosciences, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Larsson NG; Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
  • Larsson E; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden.
  • Falkenberg M; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden.
  • Taylor RW; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
  • Griffith JD; Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA.
  • Gustafsson CM; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, 405 30 Gothenburg, Sweden. Electronic address: claes.gustafsson@medkem.gu.se.
Mol Cell ; 69(1): 9-23.e6, 2018 01 04.
Article em En | MEDLINE | ID: mdl-29290614

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / DNA Topoisomerases Tipo I / Segregação de Cromossomos / Replicação do DNA / Dinâmica Mitocondrial Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / DNA Topoisomerases Tipo I / Segregação de Cromossomos / Replicação do DNA / Dinâmica Mitocondrial Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia