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Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.
Bi, Yi-An; Mathialagan, Sumathy; Tylaska, Laurie; Fu, Myra; Keefer, Julie; Vildhede, Anna; Costales, Chester; Rodrigues, A David; Varma, Manthena V S.
Afiliação
  • Bi YA; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Mathialagan S; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tylaska L; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Fu M; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Keefer J; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Vildhede A; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Costales C; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Rodrigues AD; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut.
  • Varma MVS; Pharmacokinetics Dynamics and Metabolism, Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut manthena.v.varma@pfizer.com.
J Pharmacol Exp Ther ; 364(3): 390-398, 2018 03.
Article em En | MEDLINE | ID: mdl-29326367

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tolbutamida / Transportadores de Ânions Orgânicos Sódio-Independentes / Citocromo P-450 CYP2C9 / Fígado Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tolbutamida / Transportadores de Ânions Orgânicos Sódio-Independentes / Citocromo P-450 CYP2C9 / Fígado Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2018 Tipo de documento: Article