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Weaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes.
Mulvey, Bernard; Dougherty, Joseph D.
Afiliação
  • Mulvey B; Department of Genetics, Department of Psychiatry, and the Hope Center of Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Dougherty JD; Department of Genetics, Department of Psychiatry, and the Hope Center of Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: jdougherty@genetics.wustl.edu.
Cell ; 172(1-2): 10-13, 2018 01 11.
Article em En | MEDLINE | ID: mdl-29328907
ABSTRACT
Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Estudo de Associação Genômica Ampla Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Estudo de Associação Genômica Ampla Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos