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Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.
Kwon, Young D; Chuang, Gwo-Yu; Zhang, Baoshan; Bailer, Robert T; Doria-Rose, Nicole A; Gindin, Tatyana S; Lin, Bob; Louder, Mark K; McKee, Krisha; O'Dell, Sijy; Pegu, Amarendra; Schmidt, Stephen D; Asokan, Mangaiarkarasi; Chen, Xuejun; Choe, Misook; Georgiev, Ivelin S; Jin, Vivian; Pancera, Marie; Rawi, Reda; Wang, Keyun; Chaudhuri, Rajoshi; Kueltzo, Lisa A; Manceva, Slobodanka D; Todd, John-Paul; Scorpio, Diana G; Kim, Mikyung; Reinherz, Ellis L; Wagh, Kshitij; Korber, Bette M; Connors, Mark; Shapiro, Lawrence; Mascola, John R; Kwong, Peter D.
Afiliação
  • Kwon YD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Zhang B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Gindin TS; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.
  • Lin B; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • McKee K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Pegu A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Schmidt SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Asokan M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Choe M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Georgiev IS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Jin V; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Pancera M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Rawi R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Wang K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Chaudhuri R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Kueltzo LA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Manceva SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Todd JP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Scorpio DG; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA.
  • Kim M; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Reinherz EL; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Wagh K; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • Korber BM; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • Connors M; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
  • Shapiro L; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
  • Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA. Electronic address: jmascola@nih.gov.
  • Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. Electronic address: pdkwong@nih.gov.
Cell Rep ; 22(7): 1798-1809, 2018 02 13.
Article em En | MEDLINE | ID: mdl-29444432
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Anticorpos Neutralizantes Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / HIV-1 / Anticorpos Neutralizantes Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos