Benzoquinone induces ROS-dependent mitochondria-mediated apoptosis in HL-60 cells.

Sun, Shuqiang; Zhang, Chunxiao; Gao, Jiahao; Qin, Qiongyu; Zhang, Yaya; Zhu, Hua; Yang, Xinjun; Yang, Dongren; Yan, Hongtao

Sun, Shuqiang; Zhang, Chunxiao; Gao, Jiahao; Qin, Qiongyu; Zhang, Yaya; Zhu, Hua; Yang, Xinjun; Yang, Dongren; Yan, Hongtao.

Afiliação

Sun S; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhang C; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Gao J; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Qin Q; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhang Y; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhu H; 2 School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, People's Republic of China.
Yang X; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Yang D; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.
Yan H; 1 Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, People's Republic of China.

Toxicol Ind Health ; 34(4): 270-281, 2018 Apr.

Article em En | MEDLINE | ID: mdl-29506454

Assuntos

Apoptose/efeitos dos fármacos; Benzoquinonas/farmacologia; Mitocôndrias/efeitos dos fármacos; Espécies Reativas de Oxigênio/metabolismo; Acetilcisteína/farmacologia; Caspases/metabolismo; Relação Dose-Resposta a Droga; Células HL-60; Humanos; Potencial da Membrana Mitocondrial/efeitos dos fármacos

Palavras-chave

1,â4-benzoquinone; Benzene; HL-60; apoptosis; mitochondria; reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoquinonas / Espécies Reativas de Oxigênio / Apoptose / Mitocôndrias Limite: Humans Idioma: En Revista: Toxicol Ind Health Assunto da revista: MEDICINA OCUPACIONAL / TOXICOLOGIA Ano de publicação: 2018 Tipo de documento: Article

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