Gain-of-function analysis of cis-acting diversification elements in DT40 cells.

Caldwell, Randolph B; Braselmann, Herbert; Heuer, Steffen; Schötz, Ulrike; Zitzelsberger, Horst

Caldwell, Randolph B; Braselmann, Herbert; Heuer, Steffen; Schötz, Ulrike; Zitzelsberger, Horst.

Afiliação

Caldwell RB; Department of Radiation Sciences - Research Unit Radiation Cytogenetics, Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Neuherberg, 85764, Germany.
Braselmann H; Department of Radiation Sciences - Research Unit Radiation Cytogenetics, Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Neuherberg, 85764, Germany.
Heuer S; Department of Radiation Sciences - Research Unit Radiation Cytogenetics, Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Neuherberg, 85764, Germany.
Schötz U; Department of Radiotherapy and Radiooncology, Philipps-University Marburg, University Hospital Gießen and Marburg, Marburg, 35043, Germany.
Zitzelsberger H; Department of Radiation Sciences - Research Unit Radiation Cytogenetics, Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Neuherberg, 85764, Germany.

Immunol Cell Biol ; 96(9): 948-957, 2018 10.

Article em En | MEDLINE | ID: mdl-29665088

Assuntos

Linfócitos B/imunologia; Citidina Desaminase/genética; Mutação com Ganho de Função; Switching de Imunoglobulina; Animais; Linhagem Celular; Galinhas; Conversão Gênica; Hipermutação Somática de Imunoglobulina

Palavras-chave

Activation-induced cytosine deaminase (AID AICD); DNA regulatory motifs; cis-targeting elements; immunoglobulin diversification; somatic hypermutation; transgene diversification

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Switching de Imunoglobulina / Citidina Desaminase / Mutação com Ganho de Função Limite: Animals Idioma: En Revista: Immunol Cell Biol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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