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New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action.
Vosátka, Rudolf; Krátký, Martin; Svarcová, Markéta; Janousek, Jirí; Stolaríková, Jirina; Madacki, Jan; Huszár, Stanislav; Mikusová, Katarína; Korduláková, Jana; Trejtnar, Frantisek; Vinsová, Jarmila.
Afiliação
  • Vosátka R; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic.
  • Krátký M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic.
  • Svarcová M; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic; Department of Chemistry, Faculty of Science, J. E. Purkinje University, Ceské mládeze 8, 400 96, Ústí nad Labem, Czech Republ
  • Janousek J; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic.
  • Stolaríková J; Laboratory for Mycobacterial Diagnostics and Tuberculosis, Regional Institute of Public Health in Ostrava, Partyzánské námestí 7, 702 00, Ostrava, Czech Republic.
  • Madacki J; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina CH-1, Ilkovicova 6, 842 15, Bratislava, Slovakia.
  • Huszár S; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina CH-1, Ilkovicova 6, 842 15, Bratislava, Slovakia.
  • Mikusová K; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina CH-1, Ilkovicova 6, 842 15, Bratislava, Slovakia.
  • Korduláková J; Department of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina CH-1, Ilkovicova 6, 842 15, Bratislava, Slovakia.
  • Trejtnar F; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic.
  • Vinsová J; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 500 05, Hradec Králové, Czech Republic. Electronic address: jarmila.vinsova@faf.cuni.cz.
Eur J Med Chem ; 151: 824-835, 2018 May 10.
Article em En | MEDLINE | ID: mdl-29679902
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Isoniazida / Mycobacterium tuberculosis / Antituberculosos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: República Tcheca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Isoniazida / Mycobacterium tuberculosis / Antituberculosos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: República Tcheca