Differences in initiation and discontinuation of preventive medications and use of non-pharmacological interventions after acute coronary syndrome among migrants and Danish-born.
Eur Heart J
; 39(25): 2356-2364, 2018 07 01.
Article
em En
| MEDLINE
| ID: mdl-29718168
ABSTRACT
Aims:
The aim of this article is to assess initiation and discontinuation of preventive medication and use of non-pharmacological prevention interventions after acute coronary syndrome (ACS) among migrants to Denmark compared to the local-born Danish population, taking differences in comorbidity and sociodemographic factors into account. Methods andresults:
In this large cohort study, we selected the population (n = 33 199) from nationwide registers and followed each individual among migrants and Danish-born 180 days after ACS. We identified the initiation and discontinuation of medications and the initiation and number of contacts for non-pharmacological interventions in the Register of Medicinal Products Statistics and the National Patient Register, and adjusted for comorbidity and sociodemographic factors. Non-Western migrants had lower relative risks for initiating adenosine diphosphate receptor (ADP)- and angiotensin-converting enzyme (ACE)-inhibitors (0.93, CI 0.90; 0.96, and 0.91, CI 0.87; 0.96) and patient education (0.95, CI 0.92; 0.98). Further, non-Western migrants had higher hazard ratios for discontinuing medications (statins 1.64, CI 1.45; 1.86, ADP-inhibitors 1.72, CI 1.50; 1.97, ß-blockers 1.52, CI 1.40; 1.64, and ACE-inhibitors 1.72, CI 1.46; 2.02), and fewer contacts for physical exercise and patient education (P < 0.001 and P = 0.011).Conclusion:
We identified differences between non-Western migrants and Danish-born in initiation and discontinuation of preventive medications and use of non-pharmacological interventions after ACS. These differences could not be explained by differences in comorbidity or sociodemographic factors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Migrantes
/
Síndrome Coronariana Aguda
/
Prevenção Secundária
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Eur Heart J
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Dinamarca