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Biomarker Assessment of HR Deficiency, Tumor BRCA1/2 Mutations, and CCNE1 Copy Number in Ovarian Cancer: Associations with Clinical Outcome Following Platinum Monotherapy.
Stronach, Euan A; Paul, James; Timms, Kirsten M; Hughes, Elisha; Brown, Krystal; Neff, Christopher; Perry, Michael; Gutin, Alexander; El-Bahrawy, Mona; Steel, Jennifer H; Liu, Xinxue; Lewsley, Liz-Anne; Siddiqui, Nadeem; Gabra, Hani; Lanchbury, Jerry S; Brown, Robert.
Afiliação
  • Stronach EA; Division of Cancer and Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Paul J; University of Glasgow (Cancer Research UK Clinical Trials Unit) and SGCTG, Glasgow, UK.
  • Timms KM; Myriad Genetics Inc., Salt Lake City, Utah.
  • Hughes E; Myriad Genetics Inc., Salt Lake City, Utah.
  • Brown K; Myriad Genetics Inc., Salt Lake City, Utah.
  • Neff C; Myriad Genetics Inc., Salt Lake City, Utah.
  • Perry M; Myriad Genetics Inc., Salt Lake City, Utah.
  • Gutin A; Myriad Genetics Inc., Salt Lake City, Utah.
  • El-Bahrawy M; Department of Medicine, Imperial College London, London, UK.
  • Steel JH; Division of Cancer and Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Liu X; Division of Cancer and Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Lewsley LA; University of Glasgow (Cancer Research UK Clinical Trials Unit) and SGCTG, Glasgow, UK.
  • Siddiqui N; Department of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow, UK.
  • Gabra H; Division of Cancer and Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.
  • Lanchbury JS; Early Clinical Development, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Brown R; Myriad Genetics Inc., Salt Lake City, Utah.
Mol Cancer Res ; 16(7): 1103-1111, 2018 07.
Article em En | MEDLINE | ID: mdl-29724815

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Oncogênicas / Proteína BRCA1 / Ciclina E / Proteína BRCA2 Tipo de estudo: Risk_factors_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Mol Cancer Res Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Oncogênicas / Proteína BRCA1 / Ciclina E / Proteína BRCA2 Tipo de estudo: Risk_factors_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Mol Cancer Res Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido