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The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
Mir, Rafeeq; Tonelli, Francesca; Lis, Pawel; Macartney, Thomas; Polinski, Nicole K; Martinez, Terina N; Chou, Meng-Yun; Howden, Andrew J M; König, Theresa; Hotzy, Christoph; Milenkovic, Ivan; Brücke, Thomas; Zimprich, Alexander; Sammler, Esther; Alessi, Dario R.
Afiliação
  • Mir R; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Tonelli F; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Lis P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Macartney T; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
  • Polinski NK; The Michael J. Fox Foundation for Parkinson's Research, Grand Central Station, PO Box 4777, New York, NY 10163, U.S.A.
  • Martinez TN; The Michael J. Fox Foundation for Parkinson's Research, Grand Central Station, PO Box 4777, New York, NY 10163, U.S.A.
  • Chou MY; Abcam, 863 Mitten Rd, Burlingame, CA 94010, U.S.A.
  • Howden AJM; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, U.K.
  • König T; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria.
  • Hotzy C; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria.
  • Milenkovic I; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria.
  • Brücke T; Verein zur Förderung der wissenschaftlichen Forschung im, Wilhelminenspital (FWFW), Montleartstrasse 37, 1160 Wien, Austria.
  • Zimprich A; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Wien, Austria.
  • Sammler E; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K. e.m.sammler@dundee.ac.uk d.r.alessi@dundee.ac.uk.
  • Alessi DR; Department of Neurology, School of Medicine, Dundee, Ninewells Hospital, Ninewells Drive, Dundee DD1 9SY, U.K.
Biochem J ; 475(11): 1861-1883, 2018 06 06.
Article em En | MEDLINE | ID: mdl-29743203
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas rab de Ligação ao GTP / Proteínas de Transporte Vesicular / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Limite: Animals / Humans Idioma: En Revista: Biochem J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas rab de Ligação ao GTP / Proteínas de Transporte Vesicular / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Limite: Animals / Humans Idioma: En Revista: Biochem J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido