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Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.
Sprigg, Nikola; Flaherty, Katie; Appleton, Jason P; Al-Shahi Salman, Rustam; Bereczki, Daniel; Beridze, Maia; Christensen, Hanne; Ciccone, Alfonso; Collins, Ronan; Czlonkowska, Anna; Dineen, Robert A; Duley, Lelia; Egea-Guerrero, Juan Jose; England, Timothy J; Krishnan, Kailash; Laska, Ann Charlotte; Law, Zhe Kang; Ozturk, Serefnur; Pocock, Stuart J; Roberts, Ian; Robinson, Thompson G; Roffe, Christine; Seiffge, David; Scutt, Polly; Thanabalan, Jegan; Werring, David; Whynes, David; Bath, Philip M.
Afiliação
  • Sprigg N; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK; Stroke, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK. Electronic address: nikola.sprigg@nottingham.ac.uk.
  • Flaherty K; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK.
  • Appleton JP; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK.
  • Al-Shahi Salman R; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Bereczki D; Department of Neurology, Semmelweis University, Budapest, Hungary.
  • Beridze M; The First University Clinic of Tbilisi State Medical University, Tbilisi, Georgia.
  • Christensen H; Department of Neurology, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
  • Ciccone A; Neurology Unit, Azienda Socio Sanitaria Territoriale di Mantova, Mantua, Italy.
  • Collins R; Stroke Service, Adelaide and Meath Hospital, Tallaght, Ireland.
  • Czlonkowska A; 2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
  • Dineen RA; Radiological Sciences, Division of Clinical Neuroscience, University of Nottingham, Queens Medical Centre Campus, Nottingham, UK; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.
  • Duley L; Nottingham Clinical Trials Unit, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
  • Egea-Guerrero JJ; UGC de Medicina Intensiva, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Seville, Spain.
  • England TJ; Vascular Medicine, Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Royal Derby Hospital Centre, Derby, UK.
  • Krishnan K; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK; Stroke, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK.
  • Laska AC; Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
  • Law ZK; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK; Stroke, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK; Department of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.
  • Ozturk S; Department of Neurology, Selcuk University Medical Faculty, Konya, Turkey.
  • Pocock SJ; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK.
  • Roberts I; Clinical Trials Unit, London School of Hygiene & Tropical Medicine, London, UK.
  • Robinson TG; Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
  • Roffe C; Stroke Research, Faculty of Medicine and Health Sciences, Keele University, Staffordshire, UK.
  • Seiffge D; Stroke Center, Neurology and Department of Clinical Research, University Hospital, University Basel, Basel, Switzerland.
  • Scutt P; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK.
  • Thanabalan J; Division of Neurosurgery, Department of Surgery, National University of Malaysia, Kuala Lumpur, Malaysia.
  • Werring D; Stroke Research Centre, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, University College London, London, UK.
  • Whynes D; School of Economics, University of Nottingham, University Park, Nottingham, UK.
  • Bath PM; Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, City Hospital Campus, Nottingham, UK; Stroke, Nottingham University Hospitals NHS Trust, City Hospital Campus, Nottingham, UK.
Lancet ; 391(10135): 2107-2115, 2018 05 26.
Article em En | MEDLINE | ID: mdl-29778325
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Tranexâmico / Hemorragia Cerebral / Acidente Vascular Cerebral / Antifibrinolíticos Tipo de estudo: Clinical_trials / Health_technology_assessment / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Tranexâmico / Hemorragia Cerebral / Acidente Vascular Cerebral / Antifibrinolíticos Tipo de estudo: Clinical_trials / Health_technology_assessment / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Ano de publicação: 2018 Tipo de documento: Article