Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D<sub>3</sub> Synthesis.

Jacoby, Christian; Eipper, Jens; Warnke, Markus; Tiedt, Oliver; Mergelsberg, Mario; Stärk, Hans-Joachim; Daus, Birgit; Martín-Moldes, Zaira; Zamarro, María Teresa; Díaz, Eduardo; Boll, Matthias

Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D₃ Synthesis.

Jacoby, Christian; Eipper, Jens; Warnke, Markus; Tiedt, Oliver; Mergelsberg, Mario; Stärk, Hans-Joachim; Daus, Birgit; Martín-Moldes, Zaira; Zamarro, María Teresa; Díaz, Eduardo; Boll, Matthias.

Afiliação

Jacoby C; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Eipper J; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Warnke M; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Tiedt O; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Mergelsberg M; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Stärk HJ; Department of Analytical Chemistry, Helmholtz Centre for Environmental Research UFZ, Leipzig, Germany.
Daus B; Department of Analytical Chemistry, Helmholtz Centre for Environmental Research UFZ, Leipzig, Germany.
Martín-Moldes Z; Department of Microbial and Plant Biotechnology, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.
Zamarro MT; Department of Microbial and Plant Biotechnology, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.
Díaz E; Department of Microbial and Plant Biotechnology, Centro de Investigaciones Biológicas, CSIC, Madrid, Spain.
Boll M; Faculty of Biology-Microbiology, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany matthias.boll@biologie.uni-freiburg.de.

mBio ; 9(3)2018 06 19.

Article em En | MEDLINE | ID: mdl-29921665

Assuntos

Calcifediol/síntese química; Colestanotriol 26-Mono-Oxigenase/química; Colestanotriol 26-Mono-Oxigenase/metabolismo; Molibdênio/química; Esteroides/metabolismo; Anaerobiose; Betaproteobacteria/enzimologia; Betaproteobacteria/genética; Biocatálise; Domínio Catalítico; Colestanotriol 26-Mono-Oxigenase/biossíntese; Colestanotriol 26-Mono-Oxigenase/genética; Expressão Gênica; Hidroxilação; Cinética; Chaperonas Moleculares; Oxirredução; Especificidade por Substrato; Thauera/enzimologia; Thauera/genética

Palavras-chave

alkyl hydroxylases; anaerobic catabolic pathways; molybdenum enzymes; sterols; vitamin D3 biosynthesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esteroides / Calcifediol / Colestanotriol 26-Mono-Oxigenase / Molibdênio Idioma: En Revista: MBio Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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