Early Onset Prosthetic Valve Endocarditis: Experience at a Cardiothoracic Surgical Hospital, 2006-2016.
Surg Infect (Larchmt)
; 19(5): 529-534, 2018 Jul.
Article
em En
| MEDLINE
| ID: mdl-29957138
ABSTRACT
BACKGROUND:
Early onset prosthetic valve endocarditis (EO-PVE) is an serious complication associated with heart valve replacement surgery.OBJECTIVES:
To describe the epidemiologic, clinical, and laboratory profile of patients with EO-PVE in a cardiac surgical hospital. PATIENTS ANDMETHODS:
A retrospective analysis of an endocarditis database, implemented prospectively, with a post hoc study driven by analysis of cases of adults with definite endocarditis occurring up to 12 months after heart valve surgery.RESULTS:
We identified 26 cases in 2,496 surgeries in the period 2006-2016. The average annual incidence was 1.04%. The median time between valve replacement and the diagnosis of EO-PVE was 33 days (interquartile range [IQR] 19.25-118.75). Biologic and mechanical prostheses were affected in 53.8% and 46.2%, respectively. Rheumatic disease was present in 57.7% of patients. The most common causative pathogens were Staphylococcus epidermidis (23.1%). No Staphylococcus aureus infection was reported. Complications were present in 73.1% of cases, including embolism (65.4%), acute renal failure (38.5%), and heart failure (23.1%). The mortality rate at 30 days and 12 months was 3.8% and 34.6%, respectively.CONCLUSIONS:
In our cohort EO-PVE was an serious complication of heart valve replacement with a high morbidity and mortality, despite its low frequency.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Bactérias
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Próteses Valvulares Cardíacas
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Infecções Relacionadas à Prótese
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Endocardite Bacteriana
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Valvas Cardíacas
Tipo de estudo:
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Surg Infect (Larchmt)
Assunto da revista:
BACTERIOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil