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The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.
Iezaki, Takashi; Fukasawa, Kazuya; Horie, Tetsuhiro; Park, Gyujin; Robinson, Samuel; Nakaya, Michio; Fujita, Hiroyuki; Onishi, Yuki; Ozaki, Kakeru; Kanayama, Takashi; Hiraiwa, Manami; Kitaguchi, Yuka; Kaneda, Katsuyuki; Yoneda, Yukio; Takarada, Takeshi; Guo, X Edward; Kurose, Hitoshi; Hinoi, Eiichi.
Afiliação
  • Iezaki T; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Fukasawa K; Venture Business Laboratory, Organization of Frontier Science and Innovation, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
  • Horie T; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Park G; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Robinson S; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Nakaya M; Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
  • Fujita H; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Onishi Y; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Ozaki K; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Kanayama T; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Hiraiwa M; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Kitaguchi Y; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Kaneda K; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Yoneda Y; Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa 920-1192, Japan.
  • Takarada T; Section of Prophylactic Pharmacology, Venture Business Laboratory, Organization of Frontier Science and Innovation, Kanazawa University Kanazawa, Ishikawa 920-1192, Japan.
  • Guo XE; Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
  • Kurose H; Bone Bioengineering Laboratory, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
  • Hinoi E; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Development ; 145(14)2018 07 26.
Article em En | MEDLINE | ID: mdl-29986870
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteogênese / Transdução de Sinais / Ubiquitina-Proteína Ligases / Proteína Quinase 7 Ativada por Mitógeno / Proteínas Smad / Fatores de Transcrição SOX9 Limite: Animals / Humans Idioma: En Revista: Development Assunto da revista: BIOLOGIA / EMBRIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteogênese / Transdução de Sinais / Ubiquitina-Proteína Ligases / Proteína Quinase 7 Ativada por Mitógeno / Proteínas Smad / Fatores de Transcrição SOX9 Limite: Animals / Humans Idioma: En Revista: Development Assunto da revista: BIOLOGIA / EMBRIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão