The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells.

Goldsmith, Chloe D; Bond, Danielle R; Jankowski, Helen; Weidenhofer, Judith; Stathopoulos, Costas E; Roach, Paul D; Scarlett, Christopher J

Goldsmith, Chloe D; Bond, Danielle R; Jankowski, Helen; Weidenhofer, Judith; Stathopoulos, Costas E; Roach, Paul D; Scarlett, Christopher J.

Afiliação

Goldsmith CD; Pancreatic Cancer Research Group, School of Environmental & Life Sciences, University of Newcastle, Ourimbah 2258, NSW, Australia. chloe.d.goldsmith@uon.edu.au.
Bond DR; Faculty of Science, The University of Newcastle, Ourimbah 2258, NSW, Australia. chloe.d.goldsmith@uon.edu.au.
Jankowski H; Pancreatic Cancer Research Group, School of Environmental & Life Sciences, University of Newcastle, Ourimbah 2258, NSW, Australia. Danielle.Bond@newcastle.edu.au.
Weidenhofer J; Faculty of Health, The University of Newcastle, Ourimbah 2258, NSW, Australia. Danielle.Bond@newcastle.edu.au.
Stathopoulos CE; Hunter Medical Research Institute (HMRI), New Lambton Heights 2305, NSW, Australia. Danielle.Bond@newcastle.edu.au.
Roach PD; Faculty of Health, The University of Newcastle, Ourimbah 2258, NSW, Australia. Helen.Jankowski@uon.edu.au.
Scarlett CJ; Hunter Medical Research Institute (HMRI), New Lambton Heights 2305, NSW, Australia. Helen.Jankowski@uon.edu.au.

Int J Mol Sci ; 19(7)2018 Jul 02.

Article em En | MEDLINE | ID: mdl-30004416

Assuntos

Apoptose/efeitos dos fármacos; Ciclo Celular/efeitos dos fármacos; Iridoides/farmacologia; Olea/química; Neoplasias Pancreáticas/tratamento farmacológico; Álcool Feniletílico/análogos & derivados; Proteínas Reguladoras de Apoptose/metabolismo; Linhagem Celular Tumoral; Humanos; Glucosídeos Iridoides; Iridoides/química; Proteínas de Neoplasias/metabolismo; Neoplasias Pancreáticas/metabolismo; Neoplasias Pancreáticas/patologia; Álcool Feniletílico/química; Álcool Feniletílico/farmacologia

Palavras-chave

HPDE; MIA PaCa-2; anti-cancer; chemoprevention; hydroxytyrosol; nutraceutical; oleuropein; olive; phenolic compound

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Álcool Feniletílico / Ciclo Celular / Apoptose / Olea / Iridoides Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália

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