Accelerated and high-resolution cardiac T2 mapping through peripheral k-space sharing.
Magn Reson Med
; 81(1): 220-233, 2019 01.
Article
em En
| MEDLINE
| ID: mdl-30058085
ABSTRACT
PURPOSE:
To develop high-spatial-resolution cardiac T2 mapping that allows for a reduced acquisition time while maintaining its precision. We implemented and optimized a new golden-angle radial T2 mapping technique named SKRATCH (Shared k-space Radial T2 Characterization of the Heart) that shares k-space peripheries of T2 -weighted images while preserving their contrasts.METHODS:
Six SKRATCH variants (gradient-recalled echo and balanced SSFP, free-breathing and breath-held, with and without a saturation preparation) were implemented, and their precision was compared with a navigator-gated reference technique in phantoms and 22 healthy volunteers at 3 T. The optimal breath-held SKRATCH technique was applied in a small cohort of patients with subacute myocardial infarction.RESULTS:
The faster free-breathing SKRATCH technique reduced the acquisition time by 52.4%, while maintaining the precision and spatial resolution of the reference technique. Similarly, the most precise and robust breath-held SKRATCH technique demonstrated homogenous T2 values that did not significantly differ from the navigator-gated reference (T2 = 39.9 ± 3.4 ms versus 39.5 ± 3.4 ms, P > .20, respectively). All infarct patients demonstrated a large T2 elevation in the ischemic regions of the myocardium.CONCLUSION:
The optimized SKRATCH technique enabled the accelerated acquisition of high-spatial-resolution T2 maps, was validated in healthy adult volunteers, and was successfully applied to a small initial group of patients.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Respiração
/
Coração
/
Infarto do Miocárdio
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Aged
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Magn Reson Med
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Suíça