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VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a ß1 integrin/VEGFR autocrine loop.
Boudria, Asma; Abou Faycal, Cherine; Jia, Tao; Gout, Stephanie; Keramidas, Michelle; Didier, Chloé; Lemaître, Nicolas; Manet, Sandra; Coll, Jean-Luc; Toffart, Anne-Claire; Moro-Sibilot, Denis; Albiges-Rizo, Corinne; Josserand, Véronique; Faurobert, Eva; Brambilla, Christian; Brambilla, Elisabeth; Gazzeri, Sylvie; Eymin, Beatrice.
Afiliação
  • Boudria A; INSERM U1209, UMR CNRS 5309, Team RNA splicing, Cell Signaling and Response to Therapies, Grenoble, 38042, France.
  • Abou Faycal C; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Jia T; INSERM U1209, UMR CNRS 5309, Team RNA splicing, Cell Signaling and Response to Therapies, Grenoble, 38042, France.
  • Gout S; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Keramidas M; INSERM U1209, UMR CNRS 5309, Team RNA splicing, Cell Signaling and Response to Therapies, Grenoble, 38042, France.
  • Didier C; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Lemaître N; INSERM U1209, UMR CNRS 5309, Team RNA splicing, Cell Signaling and Response to Therapies, Grenoble, 38042, France.
  • Manet S; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Coll JL; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Toffart AC; INSERM, U1209, UMR CNRS 5309, Team Cancer Targets and Experimental Therapeutics, Grenoble, 38042, France.
  • Moro-Sibilot D; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Albiges-Rizo C; INSERM, U1209, UMR CNRS 5309, Team Cancer Targets and Experimental Therapeutics, Grenoble, 38042, France.
  • Josserand V; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Faurobert E; INSERM U1209, UMR CNRS 5309, Team Tumor Molecular Pathology and Biomarkers, Grenoble, 38042, France.
  • Brambilla C; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Brambilla E; INSERM U1209, UMR CNRS 5309, Team Cell Adhesion Dynamics and Differentiation, Grenoble, 38042, France.
  • Gazzeri S; Université Grenoble Alpes, Institut Pour l'Avancée des Biosciences, Grenoble, 38041, France.
  • Eymin B; INSERM, U1209, UMR CNRS 5309, Team Cancer Targets and Experimental Therapeutics, Grenoble, 38042, France.
Oncogene ; 38(7): 1050-1066, 2019 02.
Article em En | MEDLINE | ID: mdl-30194450
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento Alternativo / Carcinoma Pulmonar de Células não Pequenas / Integrina beta1 / Comunicação Autócrina / Receptores de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Neoplasias Pulmonares / Proteínas de Neoplasias / Neovascularização Patológica Limite: Female / Humans / Male Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Processamento Alternativo / Carcinoma Pulmonar de Células não Pequenas / Integrina beta1 / Comunicação Autócrina / Receptores de Fatores de Crescimento do Endotélio Vascular / Fator A de Crescimento do Endotélio Vascular / Neoplasias Pulmonares / Proteínas de Neoplasias / Neovascularização Patológica Limite: Female / Humans / Male Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França