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Imetelstat, a telomerase inhibitor, is capable of depleting myelofibrosis stem and progenitor cells.
Wang, Xiaoli; Hu, Cing Siang; Petersen, Bruce; Qiu, Jiajing; Ye, Fei; Houldsworth, Jane; Eng, Kevin; Huang, Fei; Hoffman, Ronald.
Afiliação
  • Wang X; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Hu CS; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Petersen B; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Qiu J; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Ye F; New York Medical College, Valhalla, NY.
  • Houldsworth J; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Eng K; GRAIL Inc., Menlo Park, CA; and.
  • Huang F; Janssen Research & Development LLC, Raritan, NJ.
  • Hoffman R; Division of Hematology/Medical Oncology/Pathology, Department of Medicine, The Tisch Cancer Institute, Myeloproliferative Neoplasms Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY.
Blood Adv ; 2(18): 2378-2388, 2018 09 25.
Article em En | MEDLINE | ID: mdl-30242099

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Telomerase / Células Progenitoras Mieloides / Inibidores Enzimáticos / Mielofibrose Primária Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Blood Adv Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Telomerase / Células Progenitoras Mieloides / Inibidores Enzimáticos / Mielofibrose Primária Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Blood Adv Ano de publicação: 2018 Tipo de documento: Article