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The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice.
Murthy, Swetha E; Loud, Meaghan C; Daou, Ihab; Marshall, Kara L; Schwaller, Frederick; Kühnemund, Johannes; Francisco, Allain G; Keenan, William T; Dubin, Adrienne E; Lewin, Gary R; Patapoutian, Ardem.
Afiliação
  • Murthy SE; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Loud MC; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Daou I; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Marshall KL; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Schwaller F; Department of Neuroscience, Max Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, Berlin 13125, Germany.
  • Kühnemund J; Department of Neuroscience, Max Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, Berlin 13125, Germany.
  • Francisco AG; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Keenan WT; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Dubin AE; Howard Hughes Medical Institute, Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lewin GR; Department of Neuroscience, Max Delbrück Center for Molecular Medicine, Robert-Rössle Straße 10, Berlin 13125, Germany.
  • Patapoutian A; Excellence Cluster Neurocure, Charité Universitätsmedizin, Berlin 13125, Germany.
Sci Transl Med ; 10(462)2018 10 10.
Article em En | MEDLINE | ID: mdl-30305457
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dor / Mecanotransdução Celular / Hiperalgesia / Canais Iônicos Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dor / Mecanotransdução Celular / Hiperalgesia / Canais Iônicos Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos