In vivo neurochemical evidence that stimulation of accumbal GABA<sub>A</sub> and GABA<sub>B</sub> receptors each reduce acetylcholine efflux without affecting dopamine efflux in the nucleus accumbens of freely moving rats.

Aono, Yuri; Watanabe, Yuriko; Ishikawa, Manabu; Kuboyama, Noboru; Waddington, John L; Saigusa, Tadashi

In vivo neurochemical evidence that stimulation of accumbal GABA_A and GABA_B receptors each reduce acetylcholine efflux without affecting dopamine efflux in the nucleus accumbens of freely moving rats.

Aono, Yuri; Watanabe, Yuriko; Ishikawa, Manabu; Kuboyama, Noboru; Waddington, John L; Saigusa, Tadashi.

Afiliação

Aono Y; Department of Pharmacology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.
Watanabe Y; Oral surgery, Nihon University Graduate School of Dentistry at Matsudo, Chiba, Japan.
Ishikawa M; Department of Anesthesiology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.
Kuboyama N; Department of Pharmacology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.
Waddington JL; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Saigusa T; Department of Pharmacology, Nihon University School of Dentistry at Matsudo, Chiba, Japan.

Synapse ; 73(4): e22081, 2019 04.

Article em En | MEDLINE | ID: mdl-30450777

Assuntos

Acetilcolina/metabolismo; Agonistas de Receptores de GABA-A/farmacologia; Antagonistas de Receptores de GABA-A/farmacologia; Agonistas dos Receptores de GABA-B/farmacologia; Antagonistas de Receptores de GABA-B/farmacologia; Núcleo Accumbens/metabolismo; Animais; Baclofeno/análogos & derivados; Baclofeno/farmacologia; Bicuculina/farmacologia; Dopamina/metabolismo; Masculino; Movimento; Muscimol/farmacologia; Núcleo Accumbens/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley

Palavras-chave

GABAA receptor; GABAB receptor; acetylcholine; dopamine; microdialysis; nucleus accumbens

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilcolina / Agonistas de Receptores de GABA-A / Agonistas dos Receptores de GABA-B / Antagonistas de Receptores de GABA-A / Antagonistas de Receptores de GABA-B / Núcleo Accumbens Limite: Animals Idioma: En Revista: Synapse Assunto da revista: NEUROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

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