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Isoform selective PLD inhibition by novel, chiral 2,8-diazaspiro[4.5]decan-1-one derivatives.
Waterson, Alex G; Scott, Sarah A; Kett, Nathan R; Blobaum, Anna L; Alex Brown, H; Lindsley, Craig W.
Afiliação
  • Waterson AG; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University/Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Scott SA; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Kett NR; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA.
  • Blobaum AL; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Alex Brown H; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt Univ
  • Lindsley CW; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA; Department of Ch
Bioorg Med Chem Lett ; 28(23-24): 3670-3673, 2018 12 15.
Article em En | MEDLINE | ID: mdl-30528979
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipase D / Compostos de Espiro / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipase D / Compostos de Espiro / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos