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Secreted amyloid-ß precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Rice, Heather C; de Malmazet, Daniel; Schreurs, An; Frere, Samuel; Van Molle, Inge; Volkov, Alexander N; Creemers, Eline; Vertkin, Irena; Nys, Julie; Ranaivoson, Fanomezana M; Comoletti, Davide; Savas, Jeffrey N; Remaut, Han; Balschun, Detlef; Wierda, Keimpe D; Slutsky, Inna; Farrow, Karl; De Strooper, Bart; de Wit, Joris.
Afiliação
  • Rice HC; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • de Malmazet D; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Schreurs A; Neuro-Electronics Research Flanders, Leuven, Belgium.
  • Frere S; Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Van Molle I; Brain & Cognition, KU Leuven, Leuven, Belgium.
  • Volkov AN; Department of Physiology and Pharmacology, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
  • Creemers E; VIB-VUB Structural Biology Research Center, Brussels, Belgium.
  • Vertkin I; VIB-VUB Structural Biology Research Center, Brussels, Belgium.
  • Nys J; Jean Jeener NMR Centre, VUB, Brussels, Belgium.
  • Ranaivoson FM; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Comoletti D; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Savas JN; Department of Physiology and Pharmacology, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.
  • Remaut H; VIB Center for Brain & Disease Research, Leuven, Belgium.
  • Balschun D; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
  • Wierda KD; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
  • Slutsky I; Child Health Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
  • Farrow K; Department of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.
  • De Strooper B; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • de Wit J; VIB-VUB Structural Biology Research Center, Brussels, Belgium.
Science ; 363(6423)2019 01 11.
Article em En | MEDLINE | ID: mdl-30630900
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Precursor de Proteína beta-Amiloide / Receptores de GABA-A / Transmissão Sináptica / Plasticidade Neuronal Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Science Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Precursor de Proteína beta-Amiloide / Receptores de GABA-A / Transmissão Sináptica / Plasticidade Neuronal Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Science Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica