Anthocyanin compositions and biological activities from the red petals of Korean edible rose (Rosa hybrida cv. Noblered).
Food Chem
; 129(2): 272-278, 2011 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-30634226
ABSTRACT
The objectives of the present study were to investigate anthocyanin profiles and their biological properties, including antioxidant, anticancer, and antiallergic, from the red petals of Korean edible rose (Rosa hybrida cv. Noblered). The acidic methanol extract of this species showed potent biological activities at a concentration of 50µg/mL. Its anthocyanins were characterised as cyanidin 3,5-di-O-glucoside and pelargonidin 3,5-di-O-glucoside using reversed-phase C18 column chromatography, NMR spectroscopy, and HPLC-DAD-ESI/MS analysis. Cyanidin 3,5-di-O-glucoside was the predominant constituent (375mg/100g), representing about 85% of total content. Cyanidin 3,5-di-O-glucoside exhibited good scavenging activity against DPPH radical with IC50 value of 55.2µg/mL; pelargonidin 3,5-di-O-glucoside showed potent anticancer effects against LNCap (human prostate cell line), ACHN (human renal cell line) and MOLT-4F (human leukaemia cell line) cell cultures, with IC50 values of 6.43, 18.3, and 6.78µg/mL, respectively. Antiallergic activities were only moderate.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Food Chem
Ano de publicação:
2011
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Article