ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance.

Conrad, Catharina; Benzel, Julia; Dorzweiler, Kristina; Cook, Lena; Schlomann, Uwe; Zarbock, Alexander; Slater, Emily P; Nimsky, Christopher; Bartsch, Jörg W

Conrad, Catharina; Benzel, Julia; Dorzweiler, Kristina; Cook, Lena; Schlomann, Uwe; Zarbock, Alexander; Slater, Emily P; Nimsky, Christopher; Bartsch, Jörg W.

Afiliação

Conrad C; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.
Benzel J; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Münster D-48149, Germany.
Dorzweiler K; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.
Cook L; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.
Schlomann U; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.
Zarbock A; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.
Slater EP; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer Campus 1, Münster D-48149, Germany.
Nimsky C; Department of Visceral, Thoracic and Vascular Surgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35043, Germany.
Bartsch JW; Department of Neurosurgery, Philipps University Marburg, Baldingerstrasse, Marburg D-35033, Germany.

Clin Sci (Lond) ; 133(1): 83-99, 2019 01 15.

Article em En | MEDLINE | ID: mdl-30635388

Assuntos

Proteínas ADAM/metabolismo; Biomarcadores Tumorais/metabolismo; Movimento Celular; Resistencia a Medicamentos Antineoplásicos; Proteínas de Membrana/metabolismo; Neoplasias/enzimologia; Proteínas ADAM/antagonistas & inibidores; Animais; Antineoplásicos/uso terapêutico; Progressão da Doença; Humanos; Proteínas de Membrana/antagonistas & inibidores; Invasividade Neoplásica; Metástase Neoplásica; Neoplasias/tratamento farmacológico; Neoplasias/patologia; Inibidores de Proteases/uso terapêutico; Proteólise; Transdução de Sinais; Especificidade por Substrato

Palavras-chave

ADAM proteinases; ADAM8; Extracellular Matrix; Metastasis; Shedding; Tumor Microenvironment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Movimento Celular / Resistencia a Medicamentos Antineoplásicos / Proteínas ADAM / Proteínas de Membrana / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

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