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Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition.
Brumpton, Ben M; Fritsche, Lars G; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; Van't Hooft, Ferdinand M; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav.
Afiliação
  • Brumpton BM; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Fritsche LG; MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (B.M.B., J.Z., H.R., G.D.S.).
  • Zheng J; Clinic of Thoracic and Occupational Medicine (B.M.B.), St. Olavs Hospital, Trondheim University Hospital, Norway.
  • Nielsen JB; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Mannila M; Department of Biostatistics and Center for Statistical Genetics (L.G.F., C.W.), University of Michigan, Ann Arbor, MI.
  • Surakka I; MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (B.M.B., J.Z., H.R., G.D.S.).
  • Rasheed H; Department of Internal Medicine (J.B.N., I.S., S.E.G., C.W.), University of Michigan, Ann Arbor, MI.
  • Vie GÅ; Cardiology Unit (M.M.), Karolinska Institutet, Stockholm, Sweden.
  • Graham SE; Cardiovascular Medicine Unit, Department of Medicine Solna, Center for Molecular Medicine (M.M., F.M.v.H.), Karolinska Institutet, Stockholm, Sweden.
  • Gabrielsen ME; Department of Internal Medicine (J.B.N., I.S., S.E.G., C.W.), University of Michigan, Ann Arbor, MI.
  • Laugsand LE; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Aukrust P; MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (B.M.B., J.Z., H.R., G.D.S.).
  • Vatten LJ; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Damås JK; Department of Public Health and Nursing (G.Å.V., L.E.L., L.J.V., I.J.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Ueland T; Department of Internal Medicine (J.B.N., I.S., S.E.G., C.W.), University of Michigan, Ann Arbor, MI.
  • Janszky I; Department of Public Health and Nursing, K.G. Jebsen Center for Genetic Epidemiology (B.M.B., L.G.F., H.R., G.Å.V., M.E.G., K.H., B.O.Å.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Zwart JA; Department of Public Health and Nursing (G.Å.V., L.E.L., L.J.V., I.J.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Van't Hooft FM; Department of Circulation and Medical Imaging (L.E.L.), NTNU, Norwegian University of Science and Technology, Trondheim.
  • Seidah NG; Department of Cardiology (L.E.L.), St. Olavs Hospital, Trondheim University Hospital, Norway.
  • Hveem K; Research Institute of Internal Medicine (P.A., T.U.), Oslo University Hospital, Rikshospitalet.
  • Willer C; Section of Clinical Immunology and Infectious Diseases (P.A.), Oslo University Hospital, Rikshospitalet.
  • Smith GD; Institute of Clinical Medicine (P.A.), University of Oslo, Norway.
  • Åsvold BO; Department of Public Health and Nursing (G.Å.V., L.E.L., L.J.V., I.J.), NTNU, Norwegian University of Science and Technology, Trondheim.
Circ Genom Precis Med ; 12(1): e002335, 2019 01.
Article em En | MEDLINE | ID: mdl-30645169
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Doenças Cardiovasculares / Pró-Proteína Convertase 9 / Inibidores de PCSK9 / Hipolipemiantes Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Circ Genom Precis Med Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Doenças Cardiovasculares / Pró-Proteína Convertase 9 / Inibidores de PCSK9 / Hipolipemiantes Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Circ Genom Precis Med Ano de publicação: 2019 Tipo de documento: Article