Functional polymorphisms on chromosome 5p15.33 disturb telomere biology and confer the risk of non-small cell lung cancer in Chinese population.

Li, Ying; Xiang, Cheng; Shen, Na; Deng, Lingyan; Luo, Xia; Yuan, Peihong; Ji, Zhi; Li, Jiaoyuan; Cheng, Liming

Li, Ying; Xiang, Cheng; Shen, Na; Deng, Lingyan; Luo, Xia; Yuan, Peihong; Ji, Zhi; Li, Jiaoyuan; Cheng, Liming.

Afiliação

Li Y; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiang C; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shen N; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Deng L; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Luo X; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yuan P; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ji Z; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li J; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cheng L; Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Mol Carcinog ; 58(6): 913-921, 2019 06.

Article em En | MEDLINE | ID: mdl-30680798

Assuntos

Carcinoma Pulmonar de Células não Pequenas/genética; Cromossomos Humanos Par 5/genética; Neoplasias Pulmonares/genética; Polimorfismo de Nucleotídeo Único; Telomerase/genética; Telômero/metabolismo; Células A549; Idoso; Estudos de Casos e Controles; Linhagem Celular Tumoral; China; Feminino; Predisposição Genética para Doença; Estudo de Associação Genômica Ampla; Humanos; Masculino; Pessoa de Meia-Idade; Proteínas Proto-Oncogênicas c-myc/metabolismo; Análise de Sequência de DNA; Telomerase/metabolismo; Homeostase do Telômero

Palavras-chave

5p15.33; MYC; genetic variant; non-small cell lung cancer; telomere

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 5 / Telômero / Carcinoma Pulmonar de Células não Pequenas / Telomerase / Polimorfismo de Nucleotídeo Único / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Mol Carcinog Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google