Age­ and brain region­associated alterations of cerebral blood flow in early Alzheimer's disease assessed in AßPPSWE/PS1&#916;E9 transgenic mice using arterial spin labeling.

Guo, Yapei; Li, Xueyuan; Zhang, Min; Chen, Ningning; Wu, Shitao; Lei, Jianfeng; Wang, Zhanjing; Wang, Renzhi; Wang, Jianping; Liu, Hengfang

Age and brain regionassociated alterations of cerebral blood flow in early Alzheimer's disease assessed in AßPPSWE/PS1ΔE9 transgenic mice using arterial spin labeling.

Guo, Yapei; Li, Xueyuan; Zhang, Min; Chen, Ningning; Wu, Shitao; Lei, Jianfeng; Wang, Zhanjing; Wang, Renzhi; Wang, Jianping; Liu, Hengfang.

Afiliação

Guo Y; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Li X; Department of Neurosurgery, The First Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Zhang M; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Chen N; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Wu S; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Lei J; Center for Medical Experiments and Testing, Capital Medical University, Beijing 100069, P.R. China.
Wang Z; Center for Medical Experiments and Testing, Capital Medical University, Beijing 100069, P.R. China.
Wang R; Department of Neurosurgery, Peking Union Medical College Hospital, Beijing 100052, P.R. China.
Wang J; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Liu H; Department of Neurology, The Fifth Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.

Mol Med Rep ; 19(4): 3045-3052, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30816468

Assuntos

Doença de Alzheimer/metabolismo; Doença de Alzheimer/patologia; Precursor de Proteína beta-Amiloide/metabolismo; Encéfalo/irrigação sanguínea; Encéfalo/metabolismo; Circulação Cerebrovascular; Fatores Etários; Doença de Alzheimer/diagnóstico por imagem; Precursor de Proteína beta-Amiloide/genética; Animais; Comportamento Animal; Biomarcadores; Encéfalo/patologia; Modelos Animais de Doenças; Humanos; Imuno-Histoquímica/métodos; Imageamento por Ressonância Magnética/métodos; Camundongos; Camundongos Transgênicos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Circulação Cerebrovascular / Precursor de Proteína beta-Amiloide / Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2019 Tipo de documento: Article

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