Inhibition of a pancreatic cancer model by cooperative pairs of clinically approved and experimental antibodies.

Maron, Ruth; Schechter, Bilha; Nataraj, Nishanth Belugali; Ghosh, Soma; Romaniello, Donatella; Marrocco, Ilaria; Noronha, Ashish; Carvalho, Silvia; Yarden, Yosef; Sela, Michael

Maron, Ruth; Schechter, Bilha; Nataraj, Nishanth Belugali; Ghosh, Soma; Romaniello, Donatella; Marrocco, Ilaria; Noronha, Ashish; Carvalho, Silvia; Yarden, Yosef; Sela, Michael.

Afiliação

Maron R; Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Schechter B; Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel.
Nataraj NB; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Ghosh S; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Romaniello D; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Marrocco I; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Noronha A; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel.
Carvalho S; Israel National Center for Personalized Medicine (INCPM), Weizmann Institute of Science, Rehovot, 76100, Israel.
Yarden Y; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, 76100, Israel. Electronic address: yosef.yarden@weizmann.ac.il.
Sela M; Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel. Electronic address: michael.sela@weizmann.ac.il.

Biochem Biophys Res Commun ; 513(1): 219-225, 2019 05 21.

Article em En | MEDLINE | ID: mdl-30952434

Assuntos

Antineoplásicos Imunológicos/uso terapêutico; Cetuximab/uso terapêutico; Neoplasias Pancreáticas/tratamento farmacológico; Trastuzumab/uso terapêutico; Animais; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Modelos Animais de Doenças; Feminino; Camundongos Nus; Neoplasias Pancreáticas/patologia

Palavras-chave

EGFR/ERBB1; HER2/ERBB2; Homo-combination; Monoclonal antibody; Pancreatic cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Cetuximab / Trastuzumab / Antineoplásicos Imunológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel

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