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Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
Boza-Serrano, Antonio; Ruiz, Rocío; Sanchez-Varo, Raquel; García-Revilla, Juan; Yang, Yiyi; Jimenez-Ferrer, Itzia; Paulus, Agnes; Wennström, Malin; Vilalta, Anna; Allendorf, David; Davila, Jose Carlos; Stegmayr, John; Jiménez, Sebastian; Roca-Ceballos, Maria A; Navarro-Garrido, Victoria; Swanberg, Maria; Hsieh, Christine L; Real, Luis M; Englund, Elisabet; Linse, Sara; Leffler, Hakon; Nilsson, Ulf J; Brown, Guy C; Gutierrez, Antonia; Vitorica, Javier; Venero, Jose Luis; Deierborg, Tomas.
Afiliação
  • Boza-Serrano A; Department of Experimental Medical Science, Experimental Neuroinflammation Laboratory, Lund University, 221 84, Lund, Sweden. antonio.boza_serrano@med.lu.se.
  • Ruiz R; Departamento de Bioquímica y Biología Molecular, Instituto de Biomedicina de Sevilla (IBiS, HUVR/CSIC/Universidad de Sevilla), Universidad de Sevilla, Seville, Spain.
  • Sanchez-Varo R; Departamento de Biología Celular, Genética y Fisiología, Instituto de Investigación Biomédica de Málaga (IBIMA), Facultad de Ciencias, Universidad de Málaga, Málaga, Spain.
  • García-Revilla J; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Yang Y; Departamento de Bioquímica y Biología Molecular, Instituto de Biomedicina de Sevilla (IBiS, HUVR/CSIC/Universidad de Sevilla), Universidad de Sevilla, Seville, Spain.
  • Jimenez-Ferrer I; Department of Experimental Medical Science, Experimental Neuroinflammation Laboratory, Lund University, 221 84, Lund, Sweden.
  • Paulus A; Translational Neurogenetics Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, 221 84, Lund, Sweden.
  • Wennström M; Department of Experimental Medical Science, Experimental Neuroinflammation Laboratory, Lund University, 221 84, Lund, Sweden.
  • Vilalta A; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
  • Allendorf D; Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Davila JC; Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Stegmayr J; Departamento de Biología Celular, Genética y Fisiología, Instituto de Investigación Biomédica de Málaga (IBIMA), Facultad de Ciencias, Universidad de Málaga, Málaga, Spain.
  • Jiménez S; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Roca-Ceballos MA; Department of Laboratory Medicine, Division of Microbiology, Immunology and Glycobiology (MIG), Lund University, Lund, Sweden.
  • Navarro-Garrido V; Departamento de Bioquímica y Biología Molecular, Instituto de Biomedicina de Sevilla (IBiS, HUVR/CSIC/Universidad de Sevilla), Universidad de Sevilla, Seville, Spain.
  • Swanberg M; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Hsieh CL; Departamento de Bioquímica y Biología Molecular, Instituto de Biomedicina de Sevilla (IBiS, HUVR/CSIC/Universidad de Sevilla), Universidad de Sevilla, Seville, Spain.
  • Real LM; Departamento de Bioquímica y Biología Molecular, Instituto de Biomedicina de Sevilla (IBiS, HUVR/CSIC/Universidad de Sevilla), Universidad de Sevilla, Seville, Spain.
  • Englund E; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Linse S; Translational Neurogenetics Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, 221 84, Lund, Sweden.
  • Leffler H; Immunology Section, Department of Medicine, San Francisco VA Medical Center, UCSF School of Medicine, 4150 Clement St. 111R, San Francisco, CA, 94121, USA.
  • Nilsson UJ; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Seville, Spain.
  • Brown GC; Division of Oncology and Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Gutierrez A; Department of Biochemistry and Structural Biology, Lund University, Lund, Sweden.
  • Vitorica J; Department of Laboratory Medicine, Division of Microbiology, Immunology and Glycobiology (MIG), Lund University, Lund, Sweden.
  • Venero JL; Department of Chemistry, Centre for Analysis and Synthesis, Lund University, Lund, Sweden.
  • Deierborg T; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Acta Neuropathol ; 138(2): 251-273, 2019 08.
Article em En | MEDLINE | ID: mdl-31006066
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Galectina 3 / Doença de Alzheimer Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Galectina 3 / Doença de Alzheimer Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia