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The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming.
Sardinha-Silva, Aline; Mendonça-Natividade, Flávia C; Pinzan, Camila F; Lopes, Carla D; Costa, Diego L; Jacot, Damien; Fernandes, Fabricio F; Zorzetto-Fernandes, André L V; Gay, Nicholas J; Sher, Alan; Jankovic, Dragana; Soldati-Favre, Dominique; Grigg, Michael E; Roque-Barreira, Maria Cristina.
Afiliação
  • Sardinha-Silva A; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Mendonça-Natividade FC; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
  • Pinzan CF; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Lopes CD; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Costa DL; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Jacot D; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
  • Fernandes FF; Department of Microbiology and Molecular Medicine, CMU, University of Geneva, Switzerland.
  • Zorzetto-Fernandes ALV; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Gay NJ; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil.
  • Sher A; Department of Biochemistry, Cambridge University, United Kingdom.
  • Jankovic D; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
  • Soldati-Favre D; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
  • Grigg ME; Department of Microbiology and Molecular Medicine, CMU, University of Geneva, Switzerland.
  • Roque-Barreira MC; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.
PLoS Pathog ; 15(6): e1007871, 2019 06.
Article em En | MEDLINE | ID: mdl-31226171
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Siálicos / Toxoplasma / Células Dendríticas / Moléculas de Adesão Celular / Proteínas de Protozoários / Toxoplasmose Animal / Receptor 2 Toll-Like / Receptor 4 Toll-Like / Imunidade Inata / Macrófagos Limite: Animals Idioma: En Revista: PLoS Pathog Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Siálicos / Toxoplasma / Células Dendríticas / Moléculas de Adesão Celular / Proteínas de Protozoários / Toxoplasmose Animal / Receptor 2 Toll-Like / Receptor 4 Toll-Like / Imunidade Inata / Macrófagos Limite: Animals Idioma: En Revista: PLoS Pathog Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil