Radiographic estimation of the growth rate of initially underdiagnosed ameloblastomas.
Med Oral Patol Oral Cir Bucal
; 24(4): e468-e472, 2019 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-31232391
ABSTRACT
BACKGROUND:
To evaluate the specific growth rate (SGR) of ameloblastoma. MATERIAL ANDMETHODS:
cases of ameloblastoma initially underdiagnosed (e.g. cases overlooked or diagnosed as reactive lesions) which had adequate radiographic documentation to evaluate their progression were retrospectively selected. Two panoramic radiographs were analyzed to determine the specific growth rate (SGR) of each tumor, defined as the logarithm of the ratio of final tumor area (when the diagnosis of ameloblastoma was made) to the initial tumor area (when the lesion was underdiagnosed), divided by the time interval between the radiographic images. The tumor area was measured using the software ImageJ.RESULTS:
Twelve patients with mandibular ameloblastomas were selected, including 5 males and 7 females, with a mean age of 24.9 years (range 14-61 years). In four cases, the lesion was associated with the crown of an impacted third molar. In three cases, it was initially diagnosed as a periapical lesion. Three cases were extrafollicular and were not noticed in the initial radiographs. Two cases were initially diagnosed as ameloblastoma, but the surgery was delayed for personal reasons. The mean interval of time between the two radiographic images was 4.3 years (range 0.4-9 years). Based on our analysis, ameloblastoma grows in average 40.4% per year (range 14.9-88.7%).CONCLUSIONS:
Ameloblastoma is a progressively growing tumor, but its growth rate seems to be smaller than initially reported in the literature. Better understanding the radiographic progression of ameloblastoma might improve its early diagnosis, management, and prognosis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ameloblastoma
/
Neoplasias Mandibulares
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Med Oral Patol Oral Cir Bucal
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2019
Tipo de documento:
Article