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Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma - results of a prospective biomarker study.
Forschner, Andrea; Battke, Florian; Hadaschik, Dirk; Schulze, Martin; Weißgraeber, Stephanie; Han, Chung-Ting; Kopp, Maria; Frick, Maximilian; Klumpp, Bernhard; Tietze, Nicola; Amaral, Teresa; Martus, Peter; Sinnberg, Tobias; Eigentler, Thomas; Keim, Ulrike; Garbe, Claus; Döcker, Dennis; Biskup, Saskia.
Afiliação
  • Forschner A; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany. andrea.forschner@med.uni-tuebingen.de.
  • Battke F; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Hadaschik D; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Schulze M; Practice for Human Genetics, Tuebingen, Germany.
  • Weißgraeber S; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Han CT; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Kopp M; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Frick M; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
  • Klumpp B; Institute for Radiology, Rems-Murr-Kliniken, Winnenden, Germany.
  • Tietze N; Institute for Radiology, University Hospital Tuebingen, Tuebingen, Germany.
  • Amaral T; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany.
  • Martus P; Portuguese Air Force Health Care Direction, Lisbon, Portugal.
  • Sinnberg T; Institute for Clinical Epidemiology and applied Biostatistics (IKEaB), Tuebingen, Germany.
  • Eigentler T; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany.
  • Keim U; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany.
  • Garbe C; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany.
  • Döcker D; Center for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr. 25, 72076, Tuebingen, Germany.
  • Biskup S; Center for Genomics and Transcriptomics (CeGaT) GmbH, Tuebingen, Germany.
J Immunother Cancer ; 7(1): 180, 2019 07 12.
Article em En | MEDLINE | ID: mdl-31300034
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Antígeno CTLA-4 / Receptor de Morte Celular Programada 1 / Ipilimumab / Antineoplásicos Imunológicos / Nivolumabe / Melanoma Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Antígeno CTLA-4 / Receptor de Morte Celular Programada 1 / Ipilimumab / Antineoplásicos Imunológicos / Nivolumabe / Melanoma Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha