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Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine.
Wang, Sabrina Z; Poore, Brad; Alt, Jesse; Price, Antoinette; Allen, Sariah J; Hanaford, Allison R; Kaur, Harpreet; Orr, Brent A; Slusher, Barbara S; Eberhart, Charles G; Raabe, Eric H; Rubens, Jeffrey A.
Afiliação
  • Wang SZ; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Poore B; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Alt J; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Price A; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Allen SJ; Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Hanaford AR; Division of Neuropathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Kaur H; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Orr BA; Division of Neuropathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Slusher BS; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Eberhart CG; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
  • Raabe EH; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Rubens JA; Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, Baltimore, Maryland.
Clin Cancer Res ; 25(19): 5925-5936, 2019 10 01.
Article em En | MEDLINE | ID: mdl-31300448
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Teratoma / Proteínas Proto-Oncogênicas c-myc / Tumor Rabdoide / Diazo-Oxo-Norleucina / Glutamina Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Teratoma / Proteínas Proto-Oncogênicas c-myc / Tumor Rabdoide / Diazo-Oxo-Norleucina / Glutamina Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article