Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors.

Law, Sheonagh M; Stanfield, Samuel J; Hardisty, Gareth R; Dransfield, Ian; Campbell, Colin J; Gray, Robert D

Law, Sheonagh M; Stanfield, Samuel J; Hardisty, Gareth R; Dransfield, Ian; Campbell, Colin J; Gray, Robert D.

Afiliação

Law SM; Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, The University of Edinburgh, Edinburgh EH16 4TJ, UK.
Stanfield SJ; Joseph Black Building, The University of Edinburgh, David Brewster Rd, Edinburgh EH9 3FJ, UK.
Hardisty GR; Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, The University of Edinburgh, Edinburgh EH16 4TJ, UK.
Dransfield I; Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, The University of Edinburgh, Edinburgh EH16 4TJ, UK.
Campbell CJ; Joseph Black Building, The University of Edinburgh, David Brewster Rd, Edinburgh EH9 3FJ, UK.
Gray RD; Centre for Inflammation Research, The Queen's Medical Research Institute, 47 Little France Crescent, The University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address: r.d.gray@ed.ac.uk.

J Cyst Fibros ; 19(2): 203-210, 2020 03.

Article em En | MEDLINE | ID: mdl-31501051

Assuntos

Fibrose Cística; Macrófagos Alveolares; Fagossomos; Análise Espectral Raman; Adulto; Fenômenos Bioquímicos; Fibrose Cística/patologia; Fibrose Cística/fisiopatologia; Regulador de Condutância Transmembrana em Fibrose Cística/genética; Feminino; Corantes Fluorescentes; Humanos; Concentração de Íons de Hidrogênio; Macrófagos Alveolares/química; Macrófagos Alveolares/fisiologia; Masculino; Nanopartículas Metálicas; Nanotecnologia/instrumentação; Nanotecnologia/métodos; Fagocitose; Fagossomos/química; Fagossomos/microbiologia; Análise Espectral Raman/instrumentação; Análise Espectral Raman/métodos

Palavras-chave

Cystic fibrosis*/pathophysiology; Myeloid cells; Nanotechnology; Phagocytosis; SERS; pH

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Análise Espectral Raman / Fagossomos / Macrófagos Alveolares / Fibrose Cística Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: J Cyst Fibros Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

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