Characterization of six recombinant human RNase H2 bearing Aicardi-Goutiéres syndrome causing mutations.

Nishimura, Takuto; Baba, Misato; Ogawa, Saori; Kojima, Kenji; Takita, Teisuke; Crouch, Robert J; Yasukawa, Kiyoshi

Nishimura, Takuto; Baba, Misato; Ogawa, Saori; Kojima, Kenji; Takita, Teisuke; Crouch, Robert J; Yasukawa, Kiyoshi.

Afiliação

Nishimura T; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.
Baba M; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.
Ogawa S; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.
Kojima K; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.
Takita T; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.
Crouch RJ; Section on Formation of RNA, Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Yasukawa K; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Oiwakecho, Kitashirakawa, Sakyoku, Kyoto 606-8502, Japan.

J Biochem ; 166(6): 537-545, 2019 Dec 01.

Article em En | MEDLINE | ID: mdl-31529068

Assuntos

Doenças Autoimunes do Sistema Nervoso/genética; Malformações do Sistema Nervoso/genética; Ribonuclease H/genética; Doenças Autoimunes do Sistema Nervoso/metabolismo; Humanos; Mutação; Malformações do Sistema Nervoso/metabolismo; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo; Ribonuclease H/química; Ribonuclease H/metabolismo

Palavras-chave

AGS; activity; human RNase H2; mutation; stability

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonuclease H / Doenças Autoimunes do Sistema Nervoso / Malformações do Sistema Nervoso Limite: Humans Idioma: En Revista: J Biochem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google