Development of a Pertactin-Coated Beads Approach for Screening of Functional Monoclonal Antibodies.

He, Liwei; Yougbare, Issaka; Gajewska, Beata; Su, Jin; Leung, Rachel; Azizi, Ali

He, Liwei; Yougbare, Issaka; Gajewska, Beata; Su, Jin; Leung, Rachel; Azizi, Ali.

Afiliação

He L; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada.
Yougbare I; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada.
Gajewska B; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada.
Su J; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada.
Leung R; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada.
Azizi A; Immunology Platform, Department of Analytical Sciences North America, Sanofi Pasteur, Toronto, Ontario M2R 3T4, Canada. Electronic address: ali.azizi@sanofi.com.

J Pharm Sci ; 109(2): 1002-1007, 2020 02.

Article em En | MEDLINE | ID: mdl-31589874

Assuntos

Anticorpos Monoclonais; Fatores de Virulência de Bordetella; Animais; Anticorpos Antibacterianos; Proteínas da Membrana Bacteriana Externa; Bordetella pertussis; Humanos; Vacina contra Coqueluche

Palavras-chave

antibody(s); biopharmaceutical characterization; epitope; immunology; in vitro model(s); monoclonal antibody(s); protein(s); vaccine(s)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Virulência de Bordetella / Anticorpos Monoclonais Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: J Pharm Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá

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