A unique case of two somatic APC mutations in an early onset cribriform-morular variant of papillary thyroid carcinoma and overview of the literature.

Aydemirli, M D; van der Tuin, K; Hes, F J; van den Ouweland, A M W; van Wezel, T; Kapiteijn, E; Morreau, H

Aydemirli, M D; van der Tuin, K; Hes, F J; van den Ouweland, A M W; van Wezel, T; Kapiteijn, E; Morreau, H.

Afiliação

Aydemirli MD; Department of Medical Oncology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. M.D.Aydemirli@lumc.nl.
van der Tuin K; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Hes FJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
van den Ouweland AMW; Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands.
van Wezel T; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Kapiteijn E; Department of Medical Oncology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Morreau H; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

Fam Cancer ; 19(1): 15-21, 2020 01.

Article em En | MEDLINE | ID: mdl-31598872

Assuntos

Genes APC; Mutação; Câncer Papilífero da Tireoide/genética; Neoplasias da Glândula Tireoide/genética; Polipose Adenomatosa do Colo/genética; Feminino; Humanos; Doenças Raras/genética; Adulto Jovem; beta Catenina/genética

Palavras-chave

APC; Cribriform-morular; Cribriform-morular variant papillary thyroid carcinoma; FAP; Familial adenomatous polyposis; Thyroid carcinoma; Wnt; ß-catenin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Genes APC / Câncer Papilífero da Tireoide / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: En Revista: Fam Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

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