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Extracellular SPARC cooperates with TGF-ß signalling to induce pro-fibrotic activation of systemic sclerosis patient dermal fibroblasts.
Carvalheiro, Tiago; Malvar Fernández, Beatriz; Ottria, Andrea; Giovannone, Barbara; Marut, Wioleta; Reedquist, Kris A; Garcia, Samuel; Radstake, Timothy R.
Afiliação
  • Carvalheiro T; Department of Rheumatology and Clinical Immunology.
  • Malvar Fernández B; Laboratory of Translational Immunology.
  • Ottria A; Department of Rheumatology and Clinical Immunology.
  • Giovannone B; Laboratory of Translational Immunology.
  • Marut W; Department of Rheumatology and Clinical Immunology.
  • Reedquist KA; Laboratory of Translational Immunology.
  • Garcia S; Department of Dermatology, University Medical Centre Utrecht, University of Utrecht, Utrecht, The Netherlands.
  • Radstake TR; Department of Rheumatology and Clinical Immunology.
Rheumatology (Oxford) ; 59(9): 2258-2263, 2020 09 01.
Article em En | MEDLINE | ID: mdl-31840182

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Pele / Osteonectina / Fator de Crescimento Transformador beta1 / Fibroblastos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Pele / Osteonectina / Fator de Crescimento Transformador beta1 / Fibroblastos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2020 Tipo de documento: Article