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Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax.
Bogner, Christian; Kale, Justin; Pogmore, Justin; Chi, Xiaoke; Shamas-Din, Aisha; Fradin, Cécile; Leber, Brian; Andrews, David W.
Afiliação
  • Bogner C; Sunnybrook Research Institute, University of Toronto, Toronto, ON M5S 1A1, Canada; Third Department of Medicine, Klinikum Rechts der Isar, Technische Universität München, München 80333, Germany.
  • Kale J; Sunnybrook Research Institute, University of Toronto, Toronto, ON M5S 1A1, Canada.
  • Pogmore J; Sunnybrook Research Institute, University of Toronto, Toronto, ON M5S 1A1, Canada.
  • Chi X; Sunnybrook Research Institute, University of Toronto, Toronto, ON M5S 1A1, Canada.
  • Shamas-Din A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.
  • Fradin C; Departments of Biomedical Sciences and Biochemistry, McMaster University, Hamilton, ON L8S 4L8, Canada; Departments of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Leber B; Departments of Biomedical Sciences and Biochemistry, McMaster University, Hamilton, ON L8S 4L8, Canada; Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Andrews DW; Sunnybrook Research Institute, University of Toronto, Toronto, ON M5S 1A1, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5S 1A1, Canada; Departments of Biomedical Sciences and Biochemistry, McMaster University, Hamilton, ON L8S 4L8, Canada. Electronic address: david.a
Mol Cell ; 77(4): 901-912.e9, 2020 02 20.
Article em En | MEDLINE | ID: mdl-32001105

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína X Associada a bcl-2 / Proteína bcl-X Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína X Associada a bcl-2 / Proteína bcl-X Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha