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Phase 1 study to evaluate safety, tolerability and pharmacokinetics of a novel intra-tympanic administered thiosulfate to prevent cisplatin-induced hearing loss in cancer patients.
Viglietta, Vissia; Shi, Fuxin; Hu, Qi-Ying; Ren, Yong; Keilty, John; Wolff, Heather; McCarthy, Ryan; Kropp, Jason; Weber, Pete; Soglia, John.
Afiliação
  • Viglietta V; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA. vviglietta@decibeltx.com.
  • Shi F; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Hu QY; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Ren Y; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Keilty J; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Wolff H; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • McCarthy R; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Kropp J; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Weber P; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
  • Soglia J; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
Invest New Drugs ; 38(5): 1463-1471, 2020 10.
Article em En | MEDLINE | ID: mdl-32157599
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiossulfatos / Perda Auditiva / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiossulfatos / Perda Auditiva / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos