Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability.

Zhang, Wa; Klinkebiel, David; Barger, Carter J; Pandey, Sanjit; Guda, Chittibabu; Miller, Austin; Akers, Stacey N; Odunsi, Kunle; Karpf, Adam R

Zhang, Wa; Klinkebiel, David; Barger, Carter J; Pandey, Sanjit; Guda, Chittibabu; Miller, Austin; Akers, Stacey N; Odunsi, Kunle; Karpf, Adam R.

Afiliação

Zhang W; Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Klinkebiel D; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Barger CJ; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Pandey S; Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Guda C; Department of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Miller A; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Akers SN; Department of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Odunsi K; Department of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Karpf AR; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

Cancers (Basel) ; 12(3)2020 Mar 24.

Article em En | MEDLINE | ID: mdl-32213861

Palavras-chave

DNA hypomethylation; DNMTs; epithelial ovarian cancer; gene expression; genomic instability; repetitive elements

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Cancers (Basel) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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