Characterization of the inhibition mechanism of a tissuefactor inhibiting single-chain variable fragment: a combined computational approach.

Vermeulen, Jan-G; Burt, Felicity; van Heerden, Esta; du Preez, Louis Lategan; Meiring, Muriel

Vermeulen, Jan-G; Burt, Felicity; van Heerden, Esta; du Preez, Louis Lategan; Meiring, Muriel.

Afiliação

Vermeulen JG; Department of Microbial, Biochemical and Food Biotechnology, Faculty of Agricultural Sciences, University of the Free State, Bloemfontein, South Africa. VermeulenJ@ufs.ac.za.
Burt F; Department of Haematology and Cell Biology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa. VermeulenJ@ufs.ac.za.
van Heerden E; Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
du Preez LL; National Health Laboratory Service, Universitas, Bloemfontein, South Africa.
Meiring M; Department of Microbial, Biochemical and Food Biotechnology, Faculty of Agricultural Sciences, University of the Free State, Bloemfontein, South Africa.

J Mol Model ; 26(4): 87, 2020 Mar 26.

Article em En | MEDLINE | ID: mdl-32219568

Assuntos

Anticorpos Neutralizantes/química; Simulação de Dinâmica Molecular; Anticorpos de Cadeia Única/química; Tromboplastina/química; Humanos

Palavras-chave

Coagulation; Factor VII; Homology modeling; Molecular dynamics; Protein-protein docking; Single-chain variable fragment; Tissue factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboplastina / Anticorpos Neutralizantes / Anticorpos de Cadeia Única / Simulação de Dinâmica Molecular Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Mol Model Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: África do Sul

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