Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL-17 and IFN-Î³.

Catar, Rusan A; Chen, Lei; Cuff, Simone M; Kift-Morgan, Ann; Eberl, Matthias; Kettritz, Ralph; Kamhieh-Milz, Julian; Moll, Guido; Li, Qing; Zhao, Hongfan; Kawka, Edyta; Zickler, Daniel; Parekh, Gita; Davis, Paul; Fraser, Donald J; Dragun, Duska; Eckardt, Kai-Uwe; Jörres, Achim; Witowski, Janusz

Catar, Rusan A; Chen, Lei; Cuff, Simone M; Kift-Morgan, Ann; Eberl, Matthias; Kettritz, Ralph; Kamhieh-Milz, Julian; Moll, Guido; Li, Qing; Zhao, Hongfan; Kawka, Edyta; Zickler, Daniel; Parekh, Gita; Davis, Paul; Fraser, Donald J; Dragun, Duska; Eckardt, Kai-Uwe; Jörres, Achim; Witowski, Janusz.

Afiliação

Catar RA; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Chen L; Berlin Institute of Health, Berlin, Germany.
Cuff SM; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Kift-Morgan A; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Eberl M; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Kettritz R; Division of Infection & Immunity, School of Medicine, Cardiff University, Cardiff, UK.
Kamhieh-Milz J; Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
Moll G; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Li Q; Experimental and Clinical Research Center, Max-Delbrück-Center für Molekulare Medizin in der Helmholtz-Gemeinschaft, Berlin, Germany.
Zhao H; Department of Transfusion Medicine, Charité-Universitätsmedizin, Berlin, Germany.
Kawka E; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Zickler D; BIH Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin, Berlin, Germany.
Parekh G; Berlin-Brandenburg School for Regenerative Therapies, Charité Universitätsmedizin, Berlin, Germany.
Davis P; Julius Wolff Institute, Charité Universitätsmedizin, Berlin, Germany.
Fraser DJ; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Dragun D; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Eckardt KU; Department of Pathophysiology, Poznan University of Medical Sciences, Poznan, Poland.
Jörres A; Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin, Berlin, Germany.
Witowski J; Mologic Ltd, Bedford Technology Park, Thurleigh, Bedford, UK.

J Pathol ; 251(2): 175-186, 2020 06.

Article em En | MEDLINE | ID: mdl-32232854

Assuntos

Quimiocina CXCL1/metabolismo; Interferon gama/farmacologia; Interleucina-17/farmacologia; Infiltração de Neutrófilos/efeitos dos fármacos; Neutrófilos/efeitos dos fármacos; Peritônio/efeitos dos fármacos; Peritonite/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Células Cultivadas; Quimiocina CXCL1/genética; Feminino; Humanos; Interferon gama/metabolismo; Interleucina-17/metabolismo; Masculino; Pessoa de Meia-Idade; Neutrófilos/metabolismo; Neutrófilos/patologia; Peritônio/metabolismo; Peritônio/patologia; Peritonite/genética; Peritonite/patologia; Fator de Transcrição STAT1/metabolismo; Transdução de Sinais; Fator de Transcrição Sp1/genética; Transcrição Gênica

Palavras-chave

CXCL1; IFN-Î³; IL-17; mesothelial cells; peritoneal dialysis; peritonitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peritônio / Peritonite / Interferon gama / Interleucina-17 / Infiltração de Neutrófilos / Quimiocina CXCL1 / Neutrófilos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Pathol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

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