BIX-01294 enhanced chemotherapy effect in gastric cancer by inducing GSDME-mediated pyroptosis.

Deng, Bei-Bei; Jiao, Bao-Ping; Liu, Yang-Jun; Li, Yan-Rong; Wang, Gui-Jun

Deng, Bei-Bei; Jiao, Bao-Ping; Liu, Yang-Jun; Li, Yan-Rong; Wang, Gui-Jun.

Afiliação

Deng BB; Department of Clinical Laboratory, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Jiao BP; Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Liu YJ; Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Li YR; Department of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Wang GJ; Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.

Cell Biol Int ; 44(9): 1890-1899, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32437063

Assuntos

Azepinas/farmacologia; Piroptose/fisiologia; Quinazolinas/farmacologia; Neoplasias Gástricas/tratamento farmacológico; Animais; Apoptose/efeitos dos fármacos; Autofagia; Azepinas/metabolismo; Morte Celular; Linhagem Celular Tumoral; Sobrevivência Celular; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Proteínas de Neoplasias/metabolismo; Piroptose/efeitos dos fármacos; Quinazolinas/metabolismo; Neoplasias Gástricas/metabolismo

Palavras-chave

GSDME; autophagy; gastric cancer; pyroptosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Neoplasias Gástricas / Azepinas / Piroptose Limite: Animals Idioma: En Revista: Cell Biol Int Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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