Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?

Cinar, Elif; Yalcin-Cakmakli, Gul; Saka, Esen; Ulusoy, Ayse; Yuruker, Sinan; Elibol, Bulent; Tel, Banu C

Cinar, Elif; Yalcin-Cakmakli, Gul; Saka, Esen; Ulusoy, Ayse; Yuruker, Sinan; Elibol, Bulent; Tel, Banu C.

Afiliação

Cinar E; Department of Pharmacology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey. Electronic address: elif.cinar@hacettepe.edu.tr.
Yalcin-Cakmakli G; Department of Neurology, Hacettepe University, Sihhiye, Ankara, Turkey.
Saka E; Department of Neurology, Hacettepe University, Sihhiye, Ankara, Turkey.
Ulusoy A; German Center for Neurodegenerative Diseases, Bonn, Germany.
Yuruker S; Usak University Faculty of Medicine, Department of Histology and Embryology, Usak, Turkey.
Elibol B; Department of Neurology, Hacettepe University, Sihhiye, Ankara, Turkey.
Tel BC; Department of Pharmacology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Exp Neurol ; 330: 113357, 2020 08.

Article em En | MEDLINE | ID: mdl-32437708

Assuntos

Região CA2 Hipocampal/patologia; Disfunção Cognitiva; Modelos Animais de Doenças; Doença de Parkinson/patologia; alfa-Sinucleína/toxicidade; Animais; Giro Denteado/patologia; Feminino; Humanos; Ratos; Ratos Sprague-Dawley; Substância Negra/patologia

Palavras-chave

Adeno-associated viral vector; Alpha-synuclein; CA2 subregion; Cognitive deficits; Parkinson's disease; Synaptic dysfunction

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Modelos Animais de Doenças / Alfa-Sinucleína / Região CA2 Hipocampal / Disfunção Cognitiva Limite: Animals / Female / Humans Idioma: En Revista: Exp Neurol Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google