Determinants of the serial changes in measurements of renal allograft Doppler resistive index in the first postoperative month.
J Bras Nefrol
; 42(4): 461-466, 2020.
Article
em En, Pt
| MEDLINE
| ID: mdl-32459281
ABSTRACT
INTRODUCTION:
The role of single Doppler-derived renal resistive index (RI) in renal allograft management is still a controversial issue, however detection of changes in serial duplex scanning has been reported as more valuable. This study aimed to test the hypothesis that early change in RI following transplantation may be related to factors associated with delayed graft function (DGF). MATERIAL ANDMETHODS:
113 patients were included, in whom two RI measurements were performed within 30 days post-transplant. According to an RI change (equal to or more than 10%) in the second measurement, patients were assigned to decrease (Group I), no change (Group II), or increase (Group III) group.RESULTS:
30 subjects had a decrease, 55 had no change, and 28 had an increase in the second RI measurement. The donors were younger in Group III in comparison to Group II. In comparison to Group I, Group III had a higher frequency of deceased donor, DGF, and presence of tubular necrosis and tubular vacuolization in peri-implantation biopsies.CONCLUSION:
the increase of RI during the first weeks of the postoperative period seems to be associated with DGF and with tubular necrosis / tubular vacuolization in peri-implantation biopsies, likely related to ischemia reperfusion injury.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
Limite:
Humans
Idioma:
En
/
Pt
Revista:
J Bras Nefrol
Assunto da revista:
NEFROLOGIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Brasil