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Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-κB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models.
Selvaraju, Vaithinathan; Thirunavukkarasu, Mahesh; Joshi, Mandip; Oriowo, Babatunde; Shaikh, Inam A; Rishi, Muhammad Tipu; Tapias, Leonidas; Coca-Soliz, Vladimir; Saad, Ibnalwalid; Campbell, Jacob; Pradeep, Seetur R; Swaminathan, Santosh; Yee, Siu-Pok; McFadden, David W; Alexander Palesty, J; Maulik, Nilanjana.
Afiliação
  • Selvaraju V; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Thirunavukkarasu M; Department of Surgery, University of Connecticut Health, 263 Farmington Avenue, Farmington, 06030, CT, USA.
  • Joshi M; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Oriowo B; Department of Surgery, University of Connecticut Health, 263 Farmington Avenue, Farmington, 06030, CT, USA.
  • Shaikh IA; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Rishi MT; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
  • Tapias L; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Coca-Soliz V; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
  • Saad I; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Campbell J; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
  • Pradeep SR; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Swaminathan S; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
  • Yee SP; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • McFadden DW; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
  • Alexander Palesty J; Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, University of Connecticut Health, Farmington, 06030, CT, USA.
  • Maulik N; Department of Surgery, Saint Mary's Hospital, Waterbury, 06706, CT, USA.
Basic Res Cardiol ; 115(4): 45, 2020 06 14.
Article em En | MEDLINE | ID: mdl-32537701
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Estresse Oxidativo / Neovascularização Fisiológica / Ubiquitina-Proteína Ligases / Isquemia / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Basic Res Cardiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Estresse Oxidativo / Neovascularização Fisiológica / Ubiquitina-Proteína Ligases / Isquemia / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Basic Res Cardiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos