COVID-19 and diabetes: Insulin requirements parallel illness severity in critically unwell patients.
Clin Endocrinol (Oxf)
; 93(4): 390-393, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32683745
ABSTRACT
OBJECTIVE:
In the light of increased adverse outcomes for people with diabetes affected by COVID-19, we have described the clinical course of a cohort of critically ill patients with COVID-19 and diabetes.METHODS:
We retrospectively analysed characteristics, glucometrics and inflammatory markers of patients with diabetes mellitus admitted to intensive care unit (ICU) with COVID-19.RESULTS:
Eight patients with diabetes were admitted to ICU with COVID-19. All had type 2 diabetes, with three being newly diagnosed that admission. Mean HbA1c was 9.2%. Glucometric analysis indicated that extremely high insulin doses were required during peak inflammatory response to maintain glycaemic control with a mean peak insulin requirement of 201 units per day (2.2 units/kg/day).CONCLUSIONS:
Critically unwell patients with diabetes mellitus and COVID-19 had high insulin requirements and poorer time in target range at the time of peak inflammatory response, and this improved as their illness resolved.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estado Terminal
/
Diabetes Mellitus Tipo 2
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SARS-CoV-2
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COVID-19
/
Insulina
Tipo de estudo:
Etiology_studies
/
Incidence_studies
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Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Endocrinol (Oxf)
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Austrália