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The activities of drug inactive ingredients on biological targets.
Pottel, Joshua; Armstrong, Duncan; Zou, Ling; Fekete, Alexander; Huang, Xi-Ping; Torosyan, Hayarpi; Bednarczyk, Dallas; Whitebread, Steven; Bhhatarai, Barun; Liang, Guiqing; Jin, Hong; Ghaemi, S Nassir; Slocum, Samuel; Lukacs, Katalin V; Irwin, John J; Berg, Ellen L; Giacomini, Kathleen M; Roth, Bryan L; Shoichet, Brian K; Urban, Laszlo.
Afiliação
  • Pottel J; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.
  • Armstrong D; Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Zou L; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA.
  • Fekete A; Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Huang XP; Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27759, USA.
  • Torosyan H; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.
  • Bednarczyk D; PK Sciences, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Whitebread S; Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Bhhatarai B; PK Sciences, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Liang G; PK Sciences, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Jin H; Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Ghaemi SN; Translational Medicine, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Slocum S; Tufts University School of Medicine, Boston, MA 02111, USA.
  • Lukacs KV; Harvard Medical School, Boston, MA 02115, USA.
  • Irwin JJ; Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27759, USA.
  • Berg EL; National Heart and Lung Institute, Imperial College, London SW7 2AZ, UK.
  • Giacomini KM; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.
  • Roth BL; Eurofins, DiscoverX, South San Francisco, CA 94080, USA.
  • Shoichet BK; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA.
  • Urban L; Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27759, USA.
Science ; 369(6502): 403-413, 2020 07 24.
Article em En | MEDLINE | ID: mdl-32703874
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Composição de Medicamentos / Avaliação Pré-Clínica de Medicamentos / Excipientes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Composição de Medicamentos / Avaliação Pré-Clínica de Medicamentos / Excipientes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Science Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos