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An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Vinogradova, Ekaterina V; Zhang, Xiaoyu; Remillard, David; Lazar, Daniel C; Suciu, Radu M; Wang, Yujia; Bianco, Giulia; Yamashita, Yu; Crowley, Vincent M; Schafroth, Michael A; Yokoyama, Minoru; Konrad, David B; Lum, Kenneth M; Simon, Gabriel M; Kemper, Esther K; Lazear, Michael R; Yin, Sifei; Blewett, Megan M; Dix, Melissa M; Nguyen, Nhan; Shokhirev, Maxim N; Chin, Emily N; Lairson, Luke L; Melillo, Bruno; Schreiber, Stuart L; Forli, Stefano; Teijaro, John R; Cravatt, Benjamin F.
Afiliação
  • Vinogradova EV; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: vinograd@scripps.edu.
  • Zhang X; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Remillard D; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lazar DC; Department of Immunology and Infectious Disease, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Suciu RM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Wang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Bianco G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Yamashita Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA; Medicinal Chemistry Research Laboratories, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., 463-10 Kawauchi-cho, Tokushima 771-0192, Japan.
  • Crowley VM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Schafroth MA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Yokoyama M; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Konrad DB; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lum KM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Simon GM; Vividion Therapeutics, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Kemper EK; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lazear MR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Yin S; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Blewett MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Dix MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Nguyen N; Department of Immunology and Infectious Disease, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Shokhirev MN; Razavi Newman Integrative Genomics and Bioinformatics Core, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  • Chin EN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lairson LL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Melillo B; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02138, USA.
  • Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA 02138, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
  • Forli S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Teijaro JR; Department of Immunology and Infectious Disease, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: teijaro@scripps.edu.
  • Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: cravatt@scripps.edu.
Cell ; 182(4): 1009-1026.e29, 2020 08 20.
Article em En | MEDLINE | ID: mdl-32730809
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Cisteína / Ligantes Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Cisteína / Ligantes Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article